Repozytorium

Autor publikacji Daniela Valensin

2025

Cu(II) binding to an antimicrobial shrimp peptide - a small step for structural chemistry, a big leap for medicinal applications

Miller Adriana, Matera-Witkiewicz Agnieszka, Mikołajczyk-Tarnawa Aleksandra, Kola Arian, Wiloch Magdalena, Jonsson-Niedziolka Martin, Wieczorek Robert, Wątły Joanna, Valensin Daniela, Rowińska-Żyrek Magdalena

2025

Modulating Copper(II) Coordination and Antimicrobial Activity: Effects of d-Amino Acid Substitution and Retro-Inverso Modification in Human Saliva MUC7 Peptide

Wątły Joanna, Szarszoń Klaudia, Sabieraj Monika, Kola Arian, Wieczorek Robert, Janek Tomasz, Valensin Daniela

2025

Small Cysteine-Rich Motif, Big Function─Metal-Driven Dimerization of the CopY C-Terminal Fragment

Hecel Aleksandra, Kola Arian, Domínguez-Martín Alicia, Valensin Daniela

2024

Beyond copper: examining the significance of His-mutations in mycobacterial GroEL1 HRCT for Ni(II) complex stability and formation

Rola Anna, Kola Arian, Valensin Daniela, Palacios Oscar, Capdevila Merce, Gumienna-Kontecka Elżbieta, Potocki Sławomir

2024

Impact of metal coordination and pH on the antimicrobial activity of histatin 5 and the products of its hydrolysis

Dzień Emilia, Wątły Joanna, Kola Arian, Mikołajczyk Aleksandra, Miller Adriana, Matera-Witkiewicz Agnieszka, Valensin Daniela, Rowińska-Żyrek Magdalena

2023

Copper Forms a PPII Helix-Like Structure with the Catalytic Domains of Bacterial Zinc Metalloproteases

Potok Paulina, Kola Arian, Valensin Daniela, Capdevila Merce, Potocki Sławomir

2023

Histidine-Rich C-Terminal Tail of Mycobacterial GroEL1 and Its Copper Complex─The Impact of Point Mutations

Rola Anna, Palacios Oscar, Capdevila Merce, Valensin Daniela, Gumienna-Kontecka Elżbieta, Potocki Sławomir

2023

Semenogelins Armed in Zn(II) and Cu(II): May Bioinorganic Chemistry Help Nature to Cope with Enterococcus faecalis?

Dudek Dorota, Miller Adriana, Hecel Aleksandra, Kola Arian, Valensin Daniela, Mikołajczyk Aleksandra, Barceló-Oliver Miquel, Matera-Witkiewicz Agnieszka, Rowińska-Żyrek Magdalena

2021

Metal specificity of the Ni(II) and Zn(II) binding sites of the N-terminal and G-domain of E. coli HypB.

Hecel Aleksandra, Kola Arian, Valensin Daniela, Kozłowski Henryk, Rowińska-Żyrek Magdalena

2020

Metal complexes of two specific regions of ZnuA, a periplasmic zinc(II) transporter from Escherichia coli.

Hecel Aleksandra, Kola Arian, Valensin Daniela, Kozłowski Henryk, Rowińska-Żyrek Magdalena

2020

Zn(II)-alloferon complexes - similar sequence, different coordination modes, no antibacterial activity.

Dudek Dorota, Miller Adriana, Draghi Sara, Valensin Daniela, Mikołajczyk Aleksandra, Matera-Witkiewicz Agnieszka, Witkowska Danuta, Stokowa-Sołtys Kamila, Rowińska-Żyrek Magdalena

2019

Structural analysis of copper(I) interaction with amyloid β peptide.

De Gregorio Giuseppe, Biasotto Francesco, Hecel Aleksandra, Łuczkowski Marek, Kozłowski Henryk, Valensin Daniela

2016

Coordination and redox properties of copper interaction with α-synuclein.

Valensin Daniela, Dell'Acqua Simone, Kozłowski Henryk, Casella Luigi

2016

DOES hemopressin bind metal ions in vivo ?

Remelli Maurizio, Ceciliato Carlo, Guerrini Remo, Kołkowska Paulina, Krzywoszyńska Karolina, Salvadori Severo, Valensin Daniela, Wątły Joanna, Kozłowski Henryk

2016

Specific binding modes of Cu(I) and Ag(I) with neurotoxic domain of the human prion protein.

Valensin Daniela, Padula Emilia Maria, Hecel Aleksandra, Łuczkowski Marek, Kozłowski Henryk

2015

Impact of SDS surfactant on the interactions of Cu2+ ions with the amyloidogenic region of human prion protein.

Hecel Aleksandra, Migliorini Caterina, Valensin Daniela, Łuczkowski Marek, Kozłowski Henryk

2015

Metal ion mediated transition from random coil to β-sheet and aggregation of Bri2-23, a natural inhibitor of Aβ aggregation.

Łuczkowski Marek, de Ricco Riccardo, Stachura Monika, Potocki Sławomir, Hemmingsen Lars, Valensin Daniela

2014

Copper-induced structural propensities of the amyloidogenic region of human prion protein.

Migliorini Caterina, Sinicropi Adalgisa, Kozłowski Henryk, Łuczkowski Marek, Valensin Daniela

2014

NMR investigations of metal interactions with unstructured soluble protein domains.

de Ricco Riccardo, Potocki Sławomir, Kozłowski Henryk, Valensin Daniela

2013

Modelling of the metal binding sites in proteins involved in neurodegeneration.

Gralka Ewa K., Valensin Daniela, Remelli Maurizio, Kozłowski Henryk

2013

Prion disease.

Rowińska-Żyrek Magdalena, Valensin Daniela, Łuczkowski Marek, Kozłowski Henryk

2013

Specific metal ion binding sites in unstructured regions of proteins.

Kozłowski Henryk, Potocki Sławomir, Remelli Maurizio, Rowińska-Żyrek Magdalena, Valensin Daniela

2013

The extracellular loop of IRT1 ZIP protein - the chosen one for zinc?

Potocki Sławomir, Valensin Daniela, Camponeschi Francesca, Kozłowski Henryk

2013

The unusual stabilization of the Ni2+ and Cu2+ complexes with NSFRY.

Janicka-Kłos Anna, Porciatti Elena, Valensin Daniela, Conato Chiara, Remelli Maurizio, Oldziej Stanisław, Valensin Gianni, Kozłowski Henryk

2013

The zinc-binding fragment of HypA from Helicobacter pylori: a tempting site also for nickel ions.

Rowińska-Żyrek Magdalena, Potocki Sławomir, Witkowska Danuta, Valensin Daniela, Kozłowski Henryk

2012

Coordination of Ni2+ and Cu2+ to metal ion binding domains of E.coli SlyD protein.

Witkowska Danuta, Valensin Daniela, Rowińska-Żyrek Magdalena, Karafova Anna, Kamysz Wojciech, Kozłowski Henryk

2012

Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases).

Kozłowski Henryk, Łuczkowski Marek, Remelli Maurizio, Valensin Daniela

2012

NMR metabolomic investigation of astrocytes interacted with Aβ42 or its complexes with either copper(II) or zinc(II).

Rocchi Altea, Valensin Daniela, Aldinucci Carlo, Giani Gabriele, Barbucci Rolando, Gaggelli Elena, Kozłowski Henryk, Valensin Gianni

2012

Thermodynamic and spectroscopic investigation on the role of met residues in CuII binding to the non-octarepeat site of the human prion protein.

Remelli Maurizio, Valensin Daniela, Toso Leonardo, Gralka Ewa K., Guerrini Remo, Marzola Erika, Kozłowski Henryk

2011

Exploring the reactions of β-amyloid (Aβ) peptide 1-28 with AlIII and FeIII ions.

Valensin Daniela, Migliorini Caterina, Valensin Gianni, Gaggelli Elena, La Penna G., Kozłowski Henryk, Gabbiani C., Messori L.

2011

Metal binding ability of cysteine-rich peptide domain of ZIP13 Zn2+ ions transporter.

Potocki Sławomir, Rowińska-Żyrek Magdalena, Valensin Daniela, Krzywoszyńska Karolina, Witkowska Danuta, Łuczkowski Marek, Kozłowski Henryk

2011

The role of His-50 of α-synuclein in binding Cu(II): pH dependence, speciation, thermodynamics and structure.

Valensin Daniela, Camponeschi Francesca, Łuczkowski Marek, Baratto M. C., Remelli Maurizio, Valensin Gianni, Kozłowski Henryk

2010

Competition between histamine-like and poly-imidazole coordination sites for Cu2+ and Zn2+ ions in zebra-fish peptide of prion-like protein.

Migliorini Caterina, Witkowska Danuta, Valensin Daniela, Kamysz Wojciech, Kozłowski Henryk

2010

Copper binding to chicken and human prion protein amylodogenic regions: differences and similarities revealed by Ni2+ as a diamagnetic probe.

Valensin Daniela, Gajda K., Gralka Ewa K., Valensin Gianni, Kamysz Wojciech, Kozłowski Henryk

2010

Cu(II) ion interaction with teicoplanin-vancomycin's analog.

Brzezowska Magdalena, Kucharczyk-Klamińska Marzena, Bernardi F., Valensin Daniela, Gaggelli Nicola, Gaggelli Elena, Valensin Gianni, Jeżowska-Bojczuk Małgorzata

2010

fac-{Ru(CO)3}2+ selectively targets the histidine residues of the β-amyloid peptide 1-28. Implications for new Alzheimer's disease treatments dased on ruthenium complexes.

Valensin Daniela, Anzini P., Gaggelli Elena, Gaggelli Nicola, Tamasi G., Cini R., Gabbiani C., Michelucci E., Messori L., Kozłowski Henryk, Valensin Gianni

2010

Structural characterization and antimicrobial activity of the Zn(II) complex with P113 (demegen), a derivative of histatin 5.

Porciatti Elena, Milenković M., Gaggelli Elena, Valensin Gianni, Kozłowski Henryk, Kamysz Wojciech, Valensin Daniela

2010

The C terminus of HspA–a potential target for native Ni(II) and Bi(III) anti-ulcer drugs.

Rowińska-Żyrek Magdalena, Witkowska Danuta, Valensin Daniela, Kamysz Wojciech, Kozłowski Henryk

2009

Copper(II) coordination outside the tandem repeat region of an unstructured domain of chicken prion protein.

Gralka Ewa K., Valensin Daniela, Gajda K., Bacco D., Szyrwiel Łukasz, Remelli Maurizio, Valensin Gianni, Kamasz W., Barańska-Rybak W., Kozłowski Henryk

2009

Copper, iron, and zinc ions homeostasis and their role in neurodegenerative disorders (metal uptake, transport, distribution and regulation).

Kozłowski Henryk, Janicka-Kłos Anna, Brasuń Justyna, Gaggelli Elena, Valensin Daniela, Valensin Gianni

2009

Heteronuclear and homonuclear Cu2+ and Zn2+ complexes with multihistidine peptides based on zebrafish prion-like protein.

Valensin Daniela, Szyrwiel Łukasz, Camponeschi Francesca, Rowińska-Żyrek Magdalena, Molteni E., Jankowska Elżbieta, Szymańska Aneta, Gaggelli Elena, Valensin Gianni, Kozłowski Henryk

2009

Molecular dynamics study of the Cu2+ binding-induced "structuring" of the N-terminal domain of human prion protein.

Valensin Gianni, Molteni E., Valensin Daniela, Taraszkiewicz Magdalena P., Kozłowski Henryk

2009

Specific interactions of Bi(III) with the Cys-Xaa-Cys unit of a peptide sequence.

Rowińska-Żyrek Magdalena, Valensin Daniela, Szyrwiel Łukasz, Grzonka Z., Kozłowski Henryk

2009

Structural features of the Zn2+ complex with the single repeat region of "prion related protein" (PrP-rel-2) of zebrafish zPrP63-70 fragment.

Camponeschi Francesca, Gaggelli Elena, Kozłowski Henryk, Valensin Daniela, Valensin Gianni

2009

The complex-formation behaviour of His residues in the fifth Cu2+ binding site of human prion protein: a close look.

Remelli Maurizio, Valensin Daniela, Bacco D., Gralka Ewa K., Guerrini Remo, Migliorini Caterina, Kozłowski Henryk

2008

Binding of Ni2+ and Cu2+ ions peptides with a Cys-His motif.

Kulon Kinga, Valensin Daniela, Kamysz Wojciech, Nadolny R., Gaggelli Elena, Valensin Gianni, Kozłowski Henryk

2008

CuII binding sites located at His-96 and His-111 of the human prion protein: thermodynamic and spectroscopic studies on model peptides.

Gralka Ewa K., Valensin Daniela, Porciatti Elena, Gajda C., Gaggelli Elena, Valensin Gianni, Kamysz Wojciech, Nadolny R., Guerrini Remo, Bacco D., Remelli Maurizio, Kozłowski Henryk

2008

NMR studies of the Zn2+ interactions with rat and human β-amyloid (1-28) peptides in water-micelle environment.

Gaggelli Elena, Janicka-Kłos Anna, Jankowska Elżbieta, Kozłowski Henryk, Migliorini Caterina, Molteni E., Valensin Daniela, Valensin Gianni, Wieczerzak E.

2008

Specificity in the Cu2+ interactions with prion protein fragments and related His-rich peptides from mammals to fishes.

Kozłowski Henryk, Janicka-Kłos Anna, Stańczak Paweł, Valensin Daniela, Valensin Gianni, Kulon Kinga

2008

Structural characterization of the intra- and inter-repeat copper binding modes within the N-terminal region of "prion related protein" (PrP-rel-2) of zebrafish.

Gaggelli Elena, Jankowska Elżbieta, Kozłowski Henryk, Marcinkowska A., Migliorini Caterina, Stańczak Paweł, Valensin Daniela, Valensin Gianni

2008

Structural features of the Cu(II) complex with the rat Aβ(1-28) fragment.

Gaggelli Elena, Grzonka Z., Kozłowski Henryk, Migliorini Caterina, Molteni E., Valensin Daniela, Valensin Gianni

2008

The His-His sequence of the antimicrobial peptide demegen P-113 makes it very attractive ligand for Cu2+.

Kulon Kinga, Valensin Daniela, Kamysz Wojciech, Valensin Gianni, Nadolski P., Porciatti Elena, Gaggelli Elena, Kozłowski Henryk

2008

Zn(II) ions bind very efficiently to tandem repeat region of "prion related protein" (PrP-rel-2) of zebra-fish. MS and potentiometric evidence.

Szyrwiel Łukasz, Jankowska Elżbieta, Janicka-Kłos Anna, Szewczuk Zbigniew, Valensin Daniela, Kozłowski Henryk

2007

1H and13 C NMR study of the complex formed by copper(II) with the nucleoside antibiotic sinefungin.

Cappanelli Massimo, Gaggelli Elena, Jeżowska-Bojczuk Małgorzata, Molteni E., Mucha Ariel, Porciatti Elena, Valensin Daniela, Valensin Gianni

2007

Structural and dynamic characterization of copper(II) binding of the human prion protein outside the octarepeat region.

Berti F., Gaggelli Elena, Guerrini Remo, Janicka Anna, Kozłowski Henryk, Legowska A., Miecznikowska H., Migliorini Caterina, Pogni R., Remelli Maurizio, Rolka Krzysztof, Valensin Daniela, Valensin Gianni

2006

Metal ion binding properties of proteins related to neurodegeneration.

Kozłowski Henryk, Łuczkowski Marek, Valensin Daniela, Valensin Gianni

2006

Tandem repeat-like domain of "Similar to prion protein" (StPrP) of Japanese pufferfish binds Cu(II) as effectively as the mammalian protein.

Stańczak Paweł, Valensin Daniela, Porciatti Elena, Jankowska Elżbieta, Grzonka Z., Molteni E., Gaggelli Elena, Valensin Gianni, Kozłowski Henryk

2005

Fine tuning the structure of the Cu2+ complex with the prion protein chicken repeat by proline isomerization.

Stańczak Paweł, Valensin Daniela, Juszczyk P., Grzonka Z., Valensin Gianni, Bernardi F., Molteni E., Gaggelli Elena, Kozłowski Henryk

2005

Interaction of the human prion PrP(106-126) sequence with copper(II), manganese(II), and zinc(II): NMR and EPR studies.

Gaggelli Elena, Bernardi F., Molteni E., Pogni R., Valensin Daniela, Valensin Gianni, Remelli Maurizio, Łuczkowski Marek, Kozłowski Henryk

2005

NMR studies on Cu(II)-peptide complexes: exchange kinetics and determination of structures in solution.

Gaggelli Elena, Kozłowski Henryk, Valensin Daniela, Valensin Gianni

2005

Structure and stability of the CuII complexes with tandem repeats of the chicken prion.

Stańczak Paweł, Valensin Daniela, Juszczyk P., Grzonka Z., Migliorini Caterina, Molteni E., Valensin Gianni, Gaggelli Elena, Kozłowski Henryk

2005

Unusual binding ability of vancomycin towards Cu2+ ions.

Świątek Magdalena, Valensin Daniela, Migliorini Caterina, Gaggelli Elena, Valensin Gianni, Jeżowska-Bojczuk Małgorzata

2004

Copper binding to the neurotoxic peptide PrP106-126: termodynamic and structural studies.

Belosi B., Gaggelli Elena, Guerrini Remo, Kozłowski Henryk, Łuczkowski Marek, Mancini F., Remelli Maurizio, Valensin Daniela, Valensin Gianni

2004

Identification of a novel high affinity copper binding site in the APP(145-155) fragment of amyloid precursor protein.

Valensin Daniela, Mancini F., Łuczkowski Marek, Janicka Anna, Wiśniewska K., Gaggelli Elena, Valensin Gianni, Łankiewicz L., Kozłowski Henryk

2004

The dimeric and tetrameric octarepeat fragments of prion protein behave differently to its monomeric unit.

Valensin Daniela, Łuczkowski Marek, Mancini F., Łęgowska Anna, Gaggelli Elena, Valensin Gianni, Rolka Krzysztof, Kozłowski Henryk

2003

CuII ion coordination to an unprotected pentadecapeptide containing two his residues: competition between the terminal amino and the side-chain imidazole nitrogen donors.

Conato Chiara, Kamysz Wojciech, Kozłowski Henryk, Łuczkowski Marek, Maćkiewicz Z., Mancini F., Młynarz Piotr, Remelli Maurizio, Valensin Daniela, Valensin Gianni

2002

Cu(II) ion coordination to the pentadecapeptide model of the SPARC copper-binding site.

Conato Chiara, Kamysz Wojciech, Kozłowski Henryk, Łuczkowski Marek, Maćkiewicz Z., Młynarz Piotr, Remelli Maurizio, Valensin Daniela, Valensin Gianni

2002

Is the monomeric prion octapeptide repeat PHGGGWGQ a specific ligand for Cu2+ ions?.

Łuczkowski Marek, Kozłowski Henryk, Stawikowski M., Rolka Krzysztof, Gaggelli Elena, Valensin Daniela, Valensin Gianni

2002

Structure and dynamics of the lincomycin-copper(II) complex in water solution by 1H and 13C NMR studies.

Gaggelli Elena, Gaggelli Nicola, Valensin Daniela, Valensin Gianni, Jeżowska-Bojczuk Małgorzata, Kozłowski Henryk

2001

Co-ordination ability towards CuII of the 29-amino acid residue trypsin inhibitor of squash and two of its analogues.

Młynarz Piotr, Valensin Daniela, Kozłowski Henryk, Kowalik-Jankowska Teresa, Otlewski Jacek, Valensin Gianni, Gaggelli Nicola

2000

Chiral peptide nucleic acids having thymine and adenine in their side chain as specific ligands for NiII and CuII.

Brasuń Justyna, Ciapetti P., Kozłowski Henryk, Ołdziej S., Taddei M., Valensin Daniela, Valensin Gianni, Gaggelli Nicola