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Inne
Stereoselective preparation of chiral compounds in Mannich-type reactions of a bicyclic imine and phenols or indole.
Autorzy
Rok wydania
2014
Czasopismo
Numer woluminu
55
Strony
6619-6622
DOI
10.1016/j.tetlet.2014.10.081
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
Mannich-type reactions of a chiral bicyclic imine and various nucleophiles yield the corresponding adducts with good to high diastereoselectivity. The influence of the reaction conditions on the yield and stereochemical outcome is investigated. The configuration of the products is established by 1H NMR spectroscopy, and the major isomers of two adducts are characterized by X-ray crystallography.
Słowa kluczowe
Mannich reaction, Betti reaction, Bicyclic imines, Stereoselectivity
Adres publiczny
http://dx.doi.org/10.1016/j.tetlet.2014.10.081
Strona internetowa wydawcy
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