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To scavenge or not to scavenge: that is the quesition.
Autorzy
Rok wydania
2009
Czasopismo
Acta Crystallographica Section D: Biological Crystallography
Numer woluminu
D63
Strony
1004-1006
DOI
10.1107/S0907444909026821
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
Analysis of a series of diffraction data sets measured from four native as well as four nicotinic acid-soaked crystals of trypsin at 100 K shows a high variability in radiation-sensitivity among individual crystals for both nicotinic acid-soaked and native crystals. The level of radiation-sensitivity and the extent of its variability is statistically indistinguishable between the two conditions. This suggests that this potential scavenger does not have any statistically significant effect on the amount of radiation damage incurred in the crystals on X-ray irradiation. This is in contrast to previous results [Kauffmann et al. (2006 ▶), Structure, 14, 1099–1105] where only one crystal specimen was used for each condition (native and nicotinic acid-soaked).
Słowa kluczowe
protein crystallography, radiation damage, scavengers, nicotinic acid
Adres publiczny
https://doi.org/10.1107/S0907444909026821
Strona internetowa wydawcy
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