Repozytorium

Binding ability of Cu+2 ions by opiate-like fragments of bovine casein.

Autorzy

E. Chruścińska

Marcin Dyba

Giovanni Micera

W. Ambroziak

J. Olczak

Janusz Zabrocki

Henryk Kozłowski

Rok wydania

1997

Czasopismo

Journal of Inorganic Biochemistry

Numer woluminu

66

Strony

19-22

DOI

10.1016/s0162-0134(96)00147-x

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

The coordination modes of Cu(II) to alpha-casein (90-95) and alpha-casein (90-96) peptides with opioid activity isolated from pepsin hydrolisates of alpha-casein were investigated by means of electron paramagnetic resonance, absorption, and circular dichroism spectroscopy and potentiometry. The results allow the identification of the complex species involved and the attribution of the spectral data set to the various complex structures. According to the spectroscopic data, a phenolate side-chain of Tyr residue belonging to the Gly-Tyr-Leu or Gly-Tyr-Leu-Gln fragment of the peptides is involved in the metal coordination in a complex which is a minor species at neutral pH range.

Adres publiczny

https://doi.org/10.1016/s0162-0134(96)00147-x

Strona internetowa wydawcy

http://www.elsevier.com

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