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Metal transport and homeostasis within the human body : toxicity associated with transport abnormalities.
Autorzy
Rok wydania
2012
Czasopismo
Numer woluminu
19
Strony
2738-2759
DOI
10.2174/092986712800609698
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
In this work, latest reports about metal toxicity, transport and homeostasis have been thoroughly described and discussed. Although diseases associated with transport and homeostasis abnormalities are those of great interest, still a variety of the phenomena associated with these processes are under debate. In this paper, we try to summarize the newest theses on this topic, presenting contradictory points of view. We focus on toxic and essential metal pathways crossing and try to follow the exact metal binding molecules within the body and provide insight into the transport mechanism. Special attention is given to the mechanism of action of lately investigated metal transporters.
Słowa kluczowe
metal homeostasis, toxivity, transport
Adres publiczny
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