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LHRH interaction with Zn(II) ions.
Autorzy
Rok wydania
1989
Czasopismo
Journal of Inorganic Biochemistry
Numer woluminu
37
Strony
135-139
DOI
10.1016/0162-0134(89)80036-4
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
Luteinizing hormone-releasing hormone (LHRH), a hypothalamic neurohormone, forms a complex with Zn ions in solution. In order to explain the structure of this complex, the stability constants of Zn(II) complexes of LHRH and also pyroglutamyl-histidine-methylester, N-acetyl-histamine, and N-acetyl-histidine were established with the use of potentiometric technique. The nuclear magnetic resonance spectroscopy shows that the mode of coordination of Zn(II) to LHRH consists of binding to the imidazole nitrogen and the peptide oxygen of the His-Trp bond.
Adres publiczny
https://doi.org/10.1016/0162-0134(89)80036-4
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