Repozytorium

Carbofunctional silatrane possessing imidazole moiety: synthesis, characterization, and antibacterial studies.

Autorzy

Gurjaspreet Singh

Sheenam Girdhard

Raj Pal Sharma

Przemysław Starynowicz

Baljinder Singh

Rok wydania

2014

Czasopismo

Phosphorus, Sulfur, and Silicon and the Related Elements

Numer woluminu

189

Strony

1732-1745

DOI

10.1080/10426507.2014.902822

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

1-(3-(1-imidazol-1-yl)propyl)-2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3.0]undecane 3, with imidazole functionality containing transannular N→Si bond (2.13 Å), was synthesized by transetherification reaction of triethanolamine 1 with N-(3-propyltriethoxysilane)imidazole 2. The compound was characterized by elemental analysis, spectroscopic techniques (IR, 1H NMR, 13C NMR, UV–VIS), mass spectrometry, and X-ray diffraction. The thermal stability of silatrane 3 was studied by TGA/DTG/DSC techniques, which is in agreement with the mass spectrometry and X-ray diffraction studies. The structural investigations of 3 were complemented by quantum-chemical studies of the structure. Compound 3 showed slight activity against Escherichia coli and Staphylococcus aureus, while no activity was found against Bacillus subtillus and Vibrio cholera.

Słowa kluczowe

Imidazole, silatrane, N-(3-propyltriethoxysilane)imidazole

Adres publiczny

http://dx.doi.org/10.1080/10426507.2014.902822

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