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Bioszkła i organiczno-nieorganiczne kompozyty dla inżynierii tkankowej kości=Bioglasses and organic-inorganic composities for bone tissue engineering.
Autorzy
Rok wydania
2012
Czasopismo
Numer woluminu
66
Strony
21-39
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
Wykaz stosowanych skrótówWprowadzenie1. Morfologia i skład materiałów bioaktywnych2. krótki przegląd wybranych biomateriałów3. Synteza biomateriałów4. biomineralizacja5. Modyfikowanie powierzchni biomateriałówPodziękowaniePiśmiennictwo cytowane
The most demanded biomaterials for bone tissue engineering could be classi-fied in two main sol-gel derived groups: bioglasses and organic-inorganic compo-sites. The first of these include bioactive ceramics such as calcium phosphates (Tab. 2) [1], glasses and glass ceramics [2], and so-called inert ceramics (Tab. 1) such as Al2O3, zirconium and titanium dioxide, and carbon-based materials [3, 4]. Second-group of compounds constitute bioactive organic-inorganic hybrids, gene-rally based on organic matrix and various inorganic dopants. biomaterials in con-tact with human plasma and bone stem cells form, on their surface, hydroxyapatite Ca10(PO4)6(OH)2 (HAp) and its derivatives (Tab. 2). HAp-layer initiates bone growth and reconstruction of treated fragment (Fig. 2). These materials, due to the high degree of biocompability are considered as the most valuable compounds for bone surgery [5]. Extremely rapid development of biomaterials used in medicine caused the production of implants with different properties (Scheme 1). The real revolu-tion and technological progress have brought biomimetic composites that mimic naturally occurring solutions in living organisms. The role of such implants is not only replacing the damaged parts of body, but – due to the appropriate morphology and composition – stimulating the growth of living cells (Fig. 3) and final bone regeneration. This article is devoted to this type of biomaterials proposed for bone tissue engineering.
Słowa kluczowe
biomaterials, bioglasses, organic-inorganic hybrid, hydroxyapatite, bone implants, scaffolds, in vitro
biomateriały, bioszkła, organiczno-nieorganiczne hybrydy, hydroksyapatyt, implanty kości, rusztowania, in vitro
Adres publiczny
https://www.dbc.wroc.pl/dlibra/publication/21314/edition/19019/content?ref=desc
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