Repozytorium

Formation and isolation of an iron-tripyrrole complex from heme degradation.

Autorzy

S. P. Rath

Marylin M. Olmstead

Lechosław Latos-Grażyński

Alan L. Balch

Rok wydania

2003

Czasopismo

Journal of the American Chemical Society

Numer woluminu

125

Strony

12678-12679

DOI

10.1021/ja036656k

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

Addition of dioxygen to a solution of (py)2Fe(OEPO) (1) (where OEPO is the trianion of octaethyloxophlorin) in pyridine-d5 at 23 °C results in a series of oxidative changes that have been followed by 1H NMR spectroscopy. After 4 h, the resonances of 1 have vanished, while several sets of new resonances have developed. The most intense of these are identified as belonging to (py)2FeIII(OEB) (2) by comparison with the previously obtained spectrum of this species, which contains a ring-opened tetrapyrrole. After the sample was left standing for 1 day, further changes occur which produce a sample that is stable, because 1H NMR spectroscopic examination reveals no further changes on continued exposure to dioxygen or air. The product, (py)2FeIII(HETP) (3), where HETP is the dianion of a hexaethyltripyrrole, has been converted into (n-Bu4N)[ClFeIII(HETP)] by treatment with tetra(n-butyl)ammonium chloride. Red (n-Bu4N)[ClFeIII(HETP)] has been isolated and characterized by single-crystal X-ray diffraction.

Słowa kluczowe

Anions, Bioinorganic chemistry, Carbene compounds, Nuclear magnetic resonance spectroscopy, Pyridines

Adres publiczny

https://doi.org/10.1021/ja036656k

Strona internetowa wydawcy

https://www.acs.org/content/acs/en.html

Podobne publikacje
1997

Coupled oxidation of heme without pyridine. Formation of cyano complexes of iron oxophlorin and 5-oxaporphyrin (Verdoheme) from octaethylheme.

Balch Alan L., Koerner R., Latos-Grażyński Lechosław, Lewis J. E., Claire T. N. St., Zovinka E. P.