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Inne
Famotidine the new antiulcero-genic agent a potent ligand for metal ions.
Autorzy
Rok wydania
1992
Czasopismo
Journal of Inorganic Biochemistry
Numer woluminu
48
Strony
233-240
DOI
10.1016/0162-0134(92)84034-K
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
Potentiometric, polarographic, and spectroscopic results obtained for Cu2+ and Ni2+-famotidine systems clearly indicated that this anti-ulcerogenic drug is a very potent chelating agent able to coordinate cupric ion that was at pH below 2. This drug exhibits excellent histamine H2 receptor blocking effects and its effective coordination to metal ions may have significant biological implications. Famotidine is found to be a very effective ligand for Ni2+ ions also.
Adres publiczny
https://doi.org/10.1016/0162-0134(92)84034-K