Repozytorium

Entropy versus aromaticity in the conformational dynamics of aromatic rings.

Autorzy

Oleg V. Shishkin

Przemysław Dopieralski

Irina V. Omelchenko

Leonid Gorb

Zdzisław Latajka

Jerzy Leszczyński

Rok wydania

2013

Czasopismo

Journal of Molecular Modeling

Numer woluminu

19

Strony

4073-4077

DOI

10.1007/s00894-012-1670-2

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

Comparison of the results of Car-Parrinello molecular dynamics simulations of isolated benzene, pyrimidine and 1,2,4-triazine molecules reveals that the unusually low population of planar geometry of the benzene ring is caused by entropy effects despite its high aromaticity. The decrease in symmetry of the molecule results in smaller changes in entropy and Gibbs free energy due to out-of-plane deformations of the ring, leading to an increase in the population of planar geometry of the ring. This leads to differences in the topology of potential energy and Gibbs free energy surfaces.

Słowa kluczowe

benzene, Aromaticity, Conformational flexibility, Car-Parrinello molecular dynamics, Entropy

Adres publiczny

http://dx.doi.org/10.1007/s00894-012-1670-2

Strona internetowa wydawcy

http://link.springer.com

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