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Inne
The interaction of the ubiquitin 50-59 fragment with copper(II) ions.
Autorzy
Rok wydania
2012
Czasopismo
Journal of Inorganic Biochemistry
Numer woluminu
110
Strony
40-45
DOI
10.1016/j.jinorgbio.2011.11.001
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
In the present study, the coordination abilities of ubiquitin 50-59 fragment and its analog containing βAsp residue are discussed. The analysis is provided based on the results of potentiometric and spectroscopic measurements supported by quantum-chemical calculations. Interesting differences in the coordination of the metal cation by modified and unmodified peptides are reported. Moreover, in order to further characterize experimentally observed species, we performed quantum-chemical calculations for structures mimicking ubiquitin 50-59 fragment as a step toward a better understanding of structural and energetical aspects related to the coordination abilities of ubiquitin.
Słowa kluczowe
Coper(II) complexes, Peptides, Ubiquitin
Adres publiczny
https://doi.org/10.1016/j.jinorgbio.2011.11.001
Strona internetowa wydawcy
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