Wydział Chemii

T. Kiss

Eniko Farkas

Henryk Kozłowski

Zdzisław Siatecki

Paweł Kafarski

B. Lejczak

1989

Journal of the Chemical Society, Dalton Transactions

1053-1057

10.1039/DT9890001053

Naukowa

Angielski

Artykuł

The stoicheiometries and stability constants of the proton and copper(II) complexes of several monophosphono dipeptides (where the C-terminal carboxylate group is replaced by a phosphonate moiety) and diphosphono dipeptides (where both the C-terminal carboxylate and the N-terminal amino groups are replaced by phosphonate moieties) have been determined pH-metrically at 25°C and at an ionic strength of 0.2 mol dm^–3(KCI). From the stability data and spectral parameters of the complexes, it has been established that the PO₃^2–/CO₂^– and PO₃^2–/NH₂ substitutions do not significantly change the basic bonding modes of the simple dipeptides. However, the copper(II)-induced deprotonation and co-ordination of the peptide-amide group becomes less favoured, although, similarly to the NH₂ group, the terminal PO₃^2– group can act as an anchor to bind the metal ion and thus induce deprotonation of amide NH.

https://doi.org/10.1039/DT9890001053

https://www.rsc.org/