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Inne
Prion proteins and copper ions. Biological and chemical controversies.
Autorzy
Rok wydania
2010
Czasopismo
Numer woluminu
39
Strony
6371-6385
DOI
10.1039/c001267j
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
The Prion protein (PrP(c)) involvement in some neurodegenerative diseases is well assessed although its "normal" biological role is not completely understood. It is known that PrP(C) can bind Cu(II) ions with high specificity but the order of magnitude of the corresponding affinity constant(s) is still highly debated. This perspective is an attempt to collect the current knowledge on these topics and to build up a bridge between the biological and the chemical points of view.
Adres publiczny
http://dx.doi.org/10.1039/c001267j
Strona internetowa wydawcy
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