Repozytorium

Anthracycline anticancer drugs as effective ligands for terbium(III) ions.

Autorzy

H. B. Haj-Tayeb

M. M. L. Fiallo

A. Garnier-Suillerot

T. Kiss

Henryk Kozłowski

Rok wydania

1994

Czasopismo

Journal of the Chemical Society, Dalton Transactions

Strony

3689-3693

DOI

10.1039/DT9940003689

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

Spectroscopic measurements were carried out for terbium(III) complexes with the anthracycline anticancer drugs doxorubicin, aclarubicin, carminomycin and their simple model quinizarin-2-sulfonic acid (9,10-dihydro-1,4-dihydroxy-9,10-dioxoanthracene-2-sulfonic acid). Potentiometric titrations were carried out for the doxorubicin-, aclarubicin- and quinizarin-2-sulfonic acid-containing systems. Both stability constants and CD spectra indicate that interligand interactions stabilise the 1:2 metal-to-ligand complexes formed.

Adres publiczny

https://doi.org/10.1039/DT9940003689

Strona internetowa wydawcy

https://www.rsc.org/