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Autor publikacji V. J. Hruby
Cyclic enkephalin analogs that are hybrids of DPDPE-related peptides and Met-enkephalin-Arg-Gly-Leu: prohormone analogs that retain good potency and selectivity for δ opioid receptors.
Bartosz-Bechowski Hubert, Davis P., Slaninova J., Malatynska E., Stropova D., Porreca F., Yamamura H. I., Hruby V. J.
The effect of halogenation on blood-brain barrier permeability of a novel peptide drug.
Gentry C. L., Egleton R. D., Gillespie T. J., Abbruscato H. B, Bartosz-Bechowski Hubert, Hruby V. J., Davis T. P.
Consequences of cis-amide bond simulation in opioid peptides.
Olczak J., Kaczmarek K., Maszczyńska I., Lisowski Marek, Stropova D., Hruby V. J., Yamamura H. I., Lipkowski A. W., Zabrocki Janusz
Cyclic enkephalin analogues with exceptional potency and selectivity for δ-opioid receptors.
Hruby V. J., Bartosz-Bechowski Hubert, Davis P., Slaninova J., Zalewska T., Stropova D., Porreca F., Yamamura H. I.
Extraordinary potency of a novel delta opioid receptor agonist is due in part to increased efficacy.
Kramer T. H., Bartosz-Bechowski Hubert, Davis P., Hruby V. J., Porreca F.
Enkephalin analog prodrugs: assessment of in vitro conversion, enzyme cleavage characterization and blood-brain barrier permeability.
Greene D. L., Hau V. S., Abbruscato T. J., Bartosz-Bechowski Hubert, Misicka A., Lipkowski A. W., Hom S., Gillespie T. J., Hruby V. J., Davis T. P.
Cyclic enkephalin analogs with exceptional potency at peripheral δ opioid receptors.
Bartosz-Bechowski Hubert, Davis P., Zalewska T., Slaninova J., Porreca F., Yamamura H. I., Hruby V. J.
Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs.
Weber S. J., Abbruscato T. J., Brownson E. A., Lipkowski A. W., Polt R., Misicka A., Haaseth R. C., Bartosz-Bechowski Hubert, Hruby V. J., Davis T. P.