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Further structural analysis of GnRH complexes with metal ions.
Autorzy
Rok wydania
2005
Czasopismo
Numer woluminu
26
Strony
247-252
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
MALDI-TOF mass spectrometry, 1H NMR spectrometry, the continuous varia-tion method and molecular modeling by MM3 calculation confi rmed our earlier studies showing that gonadotropin-releasing hormone (GnRH) forms complex with copper(II) ion with the binding ratio 1:1. e copper(II) complex formed at physiological pH has a square planar confi guration and GnRH complexes with nickel(II) and cobalt(II) ions are less stable than that of copper(II).
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