Repozytorium

In vitro interaction of mutagenic chromium(VI) with red blood cells.

Autorzy

M. Branca

A. Dessi

Henryk Kozłowski

Giovanni Micera

M. V. Serra

Rok wydania

1989

Czasopismo

Febs Letters

Numer woluminu

257

Strony

52-54

DOI

10.1016/0014-5793(89)81784-3

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

The interaction of mutagenic Cr(VI) with red blood cells has been studied by ESR spectroscopy. Signals of two Cr(V) species are observed almost immediately after contacting red cells with chromate(VI) aqueous solution at pH 7.4. The signal at go = 1.985, which decays within one hour, is attributed to a Cr(V) complex formed by glutathione due its reducing and chelating ability. The other signal at go = 1.979, which is distinctly more persistent, may indicate that some immobilization of the formed Cr(V) ions takes place on the macromolecular cell components, e.g. glycoproteins.

Adres publiczny

https://doi.org/10.1016/0014-5793(89)81784-3

Strona internetowa wydawcy

onlinelibrary.wiley.com

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