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Inne
Characterization of four peptides from milk fermented with kombucha cultures and their metal complexes—in search of new biotherapeutics
Autorzy
Rok wydania
2024
Czasopismo
Frontiers in Molecular Biosciences
Numer woluminu
11
Strony
1366588/1-1366588/14
DOI
10.3389/fmolb.2024.1366588
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
The most common skin diseases include eczema, psoriasis, acne, and fungal infections. There is often no effective cure for them. Increasing antimicrobial drug resistance prompts us to search for new, safe, and effective therapeutics. Among such interesting candidates are peptides derived from milk fermented with specific lactic acid bacteria or with kombucha cultures, which are a potential treasure trove of bioactive peptides. Four of them are discussed in this article. Their interactions with zinc and copper ions, which are known to improve the well-being of the skin, were characterized by potentiometry, MS, ITC, and spectroscopic methods, and their cytostatic potential was analyzed. The results suggest that they are safe for human cells and can be used alone or in complexes with copper for further testing as potential therapeutics for skin diseases.
Słowa kluczowe
peptides, bioactivity, copper (II) ions, zinc (II) ions, spectroscopic techniques
Licencja otwartego dostępu
Licencja na prawach której można swobodnie kopiować, rozprowadzać, zmieniać i remiksować objęty prawem autorskim utwór (Utwór-przedmiot prawa autorskiego) pod warunkiem podania imienia i nazwiska autora utworu pierwotnego oraz źródła pochodzenia utworu.
Pełny tekst licencji: https://creativecommons.org/licenses/by/3.0/pl/legalcode
Adres publiczny
http://dx.doi.org/10.3389/fmolb.2024.1366588
Strona internetowa wydawcy
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