Repozytorium
Wyszukaj
Kolekcje
Inne
Open Rotaxane Surgery: What Molecular Editing Can Offer to Supramolecular Chemistry?
Autorzy
Rok wydania
2025
Czasopismo
Numer woluminu
90
Strony
e202500038/1-e202500038/3
DOI
10.1002/cplu.202500038
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
The skeletal editing approach represents a paradigm shift in organic synthesis by directly targeting the molecular skeleton instead of relying on often long and complicated series of organic transformations. Recent advancements in nitrogen atom deletion reactions have enabled unprecedented late-stage, precise modifications of bioactive compounds and complex natural products, influencing a seemingly distant field such as supramolecular chemistry. In a recent contribution, the Leigh group demonstrated the extrusion of a nitrogen atom from an axle of a [2]rotaxane, extending the applicability of molecular editing to complex, mechanically interlocked architectures. This highlight seeks to examine the significance of the skeletal editing method in supramolecular chemistry, address its challenges, and offer an outlook on future directions in this emerging field.
Słowa kluczowe
supramolecular chemistry, mechanically interlocked molecules, skeletal editing, rotaxanes
Adres publiczny
http://dx.doi.org/10.1002/cplu.202500038
Strona internetowa wydawcy
Podobne publikacje
Multimodal Molecular Motion in the Rotaxanes and Catenanes Incorporating Flexible Calix[n]phyrin Stations
Grzelczak Rafał A., Basak Tymoteusz, Trzaskowski Bartosz, Kinzhybalo Vasyl, Szyszko Bartosz
N-fusion approach in construction of contracted carbaporphyrinoids: formation of N-fused telluraporphyrin.
Pacholska-Dudziak Ewa, Ulatowski Filip, Ciunik Zbigniew, Latos-Grażyński Lechosław