Repozytorium

A potentiometric and spectroscopic study of the proton, and copper(II) and zinc(II) complexes formed by fibrinopeptide A.

Autorzy

J. F. Galey

Henryk Kozłowski

L. D. Pettit

Rok wydania

1991

Czasopismo

Journal of Inorganic Biochemistry

Numer woluminu

44

Strony

149-153

DOI

10.1016/0162-0134(91)84027-7

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

Results are reported for a potentiometric and spectroscopic (visible, CD, and EPR) study of the complexes of fibrinopeptide A (Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg) with H+, Cu2+, and Zn2+. They show that the peptide forms stable complexes with Cu2+, largely as a result of the Asp2 residue, and that its coordination behavior is almost identical to that of the N-terminal tetrapeptide fragment, Ala-Asp-Ser-Gly. Hence the influence of the remaining amino acid residues on coordination to Cu2+ is insignificant.

Adres publiczny

https://doi.org/10.1016/0162-0134(91)84027-7

Strona internetowa wydawcy

http://www.elsevier.com

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