Repozytorium

Synthesis and coordination ability of substituted imidazo-pyridines, structural analogues of oxine. Influence of copper(II) and nickel(II) ions on toxicity of the organic ligand.

Autorzy

J. Sawicka

N. Youyou

J. Świątek

P. Decock

Henryk Kozłowski

D. Blondeau

I. Lenormand

Rok wydania

1991

Czasopismo

Journal of Inorganic Biochemistry

Numer woluminu

44

Strony

117-125

DOI

10.1016/0162-0134(91)84024-4

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

Potentiometric and EPR study on Cu(II) and Ni(II) ion complexes with several imidazopyridines have shown that the oxine type of donor set, (N,O), is an effective binding site for metal ions, although the formed complexes are considerably weaker than those of oxine itself. The modification of the ligand molecule may drastically change the coordination equilibria and stabilities of the respective species. The rec-assay tests detecting the chemical's toxicity indicate that metal ion binding to organic molecules may lead to toxicity which is not observed for each of the complex components.

Adres publiczny

https://doi.org/10.1016/0162-0134(91)84024-4

Strona internetowa wydawcy

http://www.elsevier.com

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