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Inne
Silver(I) 1,3,5-triaza-7-phosphaadamantane coordination polymers driven by substituted glutarate and malonate building blocks: self-assembly synthesis, structural features, and antimicrobial properties.
Autorzy
Rok wydania
2016
Czasopismo
Numer woluminu
55
Strony
5886-5894
DOI
10.1021/acs.inorgchem.6b00186
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
Three new bioactive silver(I) coordination polymers formulated as [Ag2(μ2-PTA)(μ3-PTA)(μ2-pga)(H2O)]n·6H2O (1), [Ag2(μ2-PTA)(μ3-PTA)(Hpmal)2]n·2H2O (2), and [Ag(μ3-PTA) (Hdmga)]n (3) were self-assembled from Ag2O, 1,3,5-triaza-7-phosphaadamantane (PTA), and a substituted dicarboxylic acid (3-phenylglutaric acid (H2pga), phenylmalonic acid (H2pmal), or 3,3-dimethylglutaric acid (H2dmga)) as an ancillary ligand. Compounds 1–3 were fully characterized by IR and NMR spectroscopy, ESI-MS(±), elemental analysis, and single-crystal X-ray diffraction, revealing that their architectural and topological diversity is governed by structural modulation of a dicarboxylate building block. The structures vary from a 1D cyclic chain with the SP 1-periodic net (4,4)(0,2) topology in 2 to distinct 2D metal–organic layers with the cem-d and hcb topologies in 1 and 3, respectively. In addition, compounds 1–3 exhibit a notable antimicrobial efficiency against a panel of common Gram-negative (E. coli and P. aeruginosa) and Gram-positive (S. aureus) bacteria and yeast (C. albicans). The best normalized minimum inhibitory concentrations (normalized MIC) of 11–23 nmol mL–1 (for bacterial strains) or 68 nmol mL–1 (for a yeast strain) are shown by compound 2, and the eventual structure–bioactivity correlations are discussed.
Adres publiczny
http://dx.doi.org/10.1021/acs.inorgchem.6b00186