Repozytorium
Wyszukaj
Kolekcje
Inne
Pulse polarographic studies on metal ion interaction with DNA.
Autorzy
Rok wydania
1989
Czasopismo
Numer woluminu
1
Strony
93-104
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
The application of the differential pulse-polarography and sweep voltammetry to the studies of the metal ion interaction with DNA have shown that the local labilization of the double stranded structure of nucleic acid caused by e.g. charged surfaces may be of critical importance for such interaction. The opening of the double helix stimulates the metal ion binding to nucleic bases. This interaction is of minor importance when the intact DNA structure is available for metal ions. The polarographic techniques are very useful in the study of the local defects of the structure of the DNA molecule and of their influence on the metal ion binding. Such situation may happen on the biological membrane which is electrically charged and whose electric charge may be imitated by the mercury electrode surface.
Słowa kluczowe
Pulse Polarographic Study, Metal Ion Interaction, DNA
Adres publiczny
https://asianpubs.org/index.php/ajchem/article/view/25378/25324
Podobne publikacje
Secondary structure confirmation and localization of Mg2+ ions in the mammalian CPEB3 ribozyme.
Skilandat Miriam, Rowińska-Żyrek Magdalena, Sigel Roland K. O.
Determination of the role of specific amino acids in the binding of Zn(II), Ni(II), and Cu(II) to the active site of the M10 family metallopeptidase
Potok Paulina, Zawada Martyna, Potocki Sławomir