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Crystal-state studies on ρ-toluenesulfonates of N-oxyimides—a possible structural basis of serine proteases inhibition.
Autorzy
Rok wydania
2006
Czasopismo
Numer woluminu
30
Strony
258-265
DOI
10.1039/B513741A
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
A series of p-toluenesulfonates of N-oxyimides has been synthesized and their X-ray structures show a flattened pyramidal geometry of the hydroxyimide ring nitrogen. This structural feature is considered to be responsible for a specific chemical reactivity towards nucleophiles and inhibitory properties against proteases of these compounds.
Adres publiczny
DOI https://doi.org/10.1039/B513741A