Repozytorium

Structural characterization of derivatives of 4-methylcoumarin : theoretical and experimental studies.

Autorzy

Aleksandra Drzewiecka

Anna E. Kozioł

Marta Struga

Tomas Pena Ruiz

Manuel Fernandez Gomez

Tadeusz Lis

Rok wydania

2013

Czasopismo

Journal of Molecular Structure

Numer woluminu

1043

Strony

109-115

DOI

10.1016/j.molstruc.2013.04.007

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

The quantum chemical conformational analysis was performed for 4-methylcoumarin derivatives substituted with the hydroxy, acetyl and/or alkoxy groups. Their crystal structures were determined by a single crystal X-ray crystallography. The structural data in the solid were compared with the results of the quantum chemical analysis in the gas phase. The results indicated that the coumarin system is nearly planar and several conformers differing in the orientation of the methoxy and acetyl groups are observed. The stereochemistry of the lowest energy rotamers in the gas phase is retained in solid state; intermolecular forces are to weak for inducing conformational changes. In the crystals of studied 4-methylcoumarin derivatives the π⋯π stacking of benzopyran systems is a very characteristic and persistent feature of the molecular association. The extend of the π⋯π overlapping depends on substituents.

Słowa kluczowe

Coumarin derivatives, DFT calculation, crystal structure, π⋯π Interactions

Adres publiczny

http://dx.doi.org/10.1016/j.molstruc.2013.04.007

Strona internetowa wydawcy

http://www.elsevier.com

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