Repozytorium

Specific structure-stability relations in metallopeptides.

Autorzy

Henryk Kozłowski

Wojciech Bal

Marcin Dyba

Teresa Kowalik-Jankowska

Rok wydania

1999

Czasopismo

Coordination Chemistry Reviews

Numer woluminu

184

Strony

319-346

DOI

10.1016/S0010-8545(98)00261-6

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

This review discusses the modes of coordination of oligopeptides by Cu(II) and Ni(II). Special attention is given to two general classes of peptides. The first part of the review deals with indirect effects introduced by special sequences of non-bonding side-chains. Unusual coordination modes resulting from the introduction of the break-point proline residues are also discussed. The second part of the review describes the binding properties of histidine peptides. The effects of the positioning of a His residue are discussed in the terms of cooperation and competition between potential metal anchoring sites. Special attention is given to His-3 peptides, modeling the biologically relevant albumin-like metal binding site. Finally, the coordination-related specific hydrolysis processes in histidine peptides are briefly discussed.

Słowa kluczowe

Metallopeptides, The proline break-point, Structure–stability relations

Adres publiczny

https://doi.org/10.1016/S0010-8545(98)00261-6

Strona internetowa wydawcy

http://www.elsevier.com

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