Repozytorium
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Inne
Fusobacterium nucleatum – Friend or foe?
Autorzy
Rok wydania
2021
Czasopismo
Journal of Inorganic Biochemistry
Numer woluminu
224
Strony
111586/1-111586/10
DOI
10.1016/j.jinorgbio.2021.111586
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
Fusobacterium nucleatum (F. nucleatum) is one of the most abundant Gram-negative anaerobic bacteria, part of the gut, and oral commensal flora, generally found in human dental plaque. Its presence could be associated with various human diseases, including, e.g., periodontal, angina, lung and gynecological abscesses. This bacteria can enter the blood circulation as a result of periodontal infection. It was proven that F. nucleatum migrates from its primary site of colonization in the oral cavity to other parts of the body. It could cause numerous diseases, including cancers. On the other hand, it was shown that Fusobacterium produces significant amounts of butyric acid, which is a great source of energy for colonocytes (anti-inflammatory cells). Therefore, it is very interesting to get to know the two faces of F. nucleatum.
Słowa kluczowe
Fusobacterium nucleatum, Commensal bacteria, cancer progression, Reactive oxygen species
Adres publiczny
http://dx.doi.org/10.1016/j.jinorgbio.2021.111586
Strona internetowa wydawcy
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