Repozytorium

α-Amination and the 5-exo-trig cyclization reaction of sulfur-containing Schiff bases with N-phenyltriazolinedione and their anti-lipid peroxidation activity.

Autorzy

Emel Pelit

Kosmas Oikonomou

Melek Gül

Dimitra Georgiou

Sławomir Szafert

Sotirios Katsamakas

Dimitra Hadjipavlou-Litina

Yiannis Elemes

Rok wydania

2017

Czasopismo

Comptes Rendus Chimie

Numer woluminu

20

Strony

424-434

DOI

10.1016/j.crci.2016.05.024

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

Triazolinedione quenches efficiently the 1,2-dipoles from Schiff bases of glycine esters which are formed via a [1,2-H]-prototropic shift of their α-hydrogens, and affords the respective α-aminated products in good yields. Competition experiments show a stabilization of the 1,2-dipole from the sulfide substituent. 5-exo-trig cyclization of N-PhTAD with Schiff bases of other amino acids gave triazolines. The antioxidative and lipoxygenase inhibitory activities of the novel synthesized compounds were studied.

Słowa kluczowe

Triazolinedione, atom, amino acid, Schiff-base, α-Amination, photoluminescence

Adres publiczny

https://doi.org/10.1016/j.crci.2016.05.024

Strona internetowa wydawcy

http://www.elsevier.com

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