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Inne
The mimetics of antiadhesive peptides as the inhibitors of Mycobacterium kansasii phagocytosis.
Autorzy
Rok wydania
2005
Czasopismo
Numer woluminu
26
Strony
1543-1549
DOI
10.1016/j.peptides.2005.02.009
Kolekcja
Język
Angielski
Typ publikacji
Artykuł
The α-guanidino acids derived of 15 proteinaceous amino acids, ω-guanidino acids with gradually increased hydrocarbon chains, and amidinated dipeptides, were tested as the mimetics of antiadhesive peptides in Mycobacteria phagocytosis inhibition. The crystal structure of ω-guanidino acids used was determined by X-ray structural analysis. It follows from our experiments that the proper distance between guanidine and carboxyl groups of effector molecules is of decisive importance for their inhibitory activity.
Słowa kluczowe
Antiadhesive peptides, Peptide mimetics, Mycobacteria phagocytosis, Guanidino acids
Adres publiczny
https://doi.org/10.1016/j.peptides.2005.02.009
Strona internetowa wydawcy
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