Repozytorium

Experimental evidence on interaction between xenon and bovine serum albumin.

Autorzy

Łukasz Wołoszyn

Marek Ilczyszyn

Maria M. Ilczyszyn

Rok wydania

2014

Czasopismo

Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy

Numer woluminu

125

Strony

449-452

DOI

10.1016/j.saa.2014.02.062

Kolekcja

Naukowa

Język

Angielski

Typ publikacji

Artykuł

Streszczenie

Xenon gas interacts with bovine serum albumin (BSA) dissolved in a physiological buffer solution. The fluorescence quenching related to the Trp emission is reversible and depends linearly on the time of saturation by Xe. The most probable site of this interaction is Trp212. The common emission of all BSA fluorophores is also influenced by Xe but this quenching is more complex and suggests: (i) at least two sites occupied by Xe and related to the Tyr and Trp residues; (ii) structural variations of BSA induced by the Xe guest atoms.

Słowa kluczowe

Albumin, Xenon, anesthesia, fluorescence, supramolecular interactions

Adres publiczny

http://dx.doi.org/10.1016/j.saa.2014.02.062

Strona internetowa wydawcy

http://www.elsevier.com

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